| 14 Aug 2025 | 20:30 | Amical | CPB Rennes Handball |  | 37 - 26 |  | Lanester | Salle du Foso - Vannes | | | |
| 16 Aug 2025 | 19:00 | Amical | CPB Rennes Handball | | 24 - 21 |  | HBC Nantes | Salle Charles Géniaux - Rennes | | | |
| 23 Aug 2025 | 16:30 | Amical | Bouguenais (N2) |  | 13 - 21 | | CPB Rennes Handball | Salle Henri Fogel - St Nazaire | | | |
| 23 Aug 2025 | 14:15 | Amical | Saint-Nazaire |  | 27 - 26 | | CPB Rennes Handball | Salle Henri Fogel - St Nazaire | | | |
| 30 Aug 2025 | 19:00 |  | Chantepie (N3) |  | 26 - 38 | | CPB Rennes Handball | Cosec des Deux Ruisseaux - Chantepie | |  | |
| 13 Sep 2025 | 20:45 |  | CPB Rennes Handball | | 36 - 36 |  | Saint-Ouen l'Aumone | Salle Charles Géniaux - Rennes |  | |  |
| 20 Sep 2025 | 20:45 | | CPB Rennes Handball | | 36 - 35 |  | Gonfreville l'Orcher | Salle Charles Géniaux - Rennes | | | |
| 28 Sep 2025 | 16:00 | | Caen |  | 33-24 | | CPB Rennes Handball | Halle Saint Jean-Eudes - Caen | | | |
| 4 Oct 2025 | 20:45 | | CPB Rennes Handball | | 23-26 |  | Bruges | Salle Charles Géniaux - Rennes | | | |
| 18 Oct 2025 | 20H30 | | Chartres
|  | 26-28 | | CPB Rennes Handball | Halle Jean Cochet - Chartres | | | |
| 25 Oct 2025 | 20:45 | | CPB Rennes Handball | | 29-26 |  | Nantes | Salle Charles Géniaux - Rennes | | | |
| 1 Nov 2025 | 19:00 | | AL Loudéac (N3) |  | 29-36 | | CPB Rennes Handball | Palais des Sports - Loudéac | | | |
| 8 Nov 2025 | 20:30 | | Libourne |  | 35-30 | | CPB Rennes Handball | Salle Kany - Libourne | | | |
| 15 Nov 2025 | 20:45 | | CPB Rennes Handball | | 24-23 |  | Poitiers | Salle Charles Géniaux - Rennes | | | |
| 22 Nov 2025 | 21:00 | | Union Sud Mayenne |  | 32-20 | | CPB Rennes Handball | Le Pressoiras - Chateau-Gontier | | | |
| 6 Dec 2025 | 20:45 | | CPB Rennes Handball | | 28-28 |  | Hennebont-Lochrist | Salle Charles Géniaux - Rennes | | | |
| 13 Dec 2025 | 18:30 | | Rouen |  | 33-27 | | CPB Rennes Handball | KindArena - Rouen | | | |
| 20 Dec 2025 | 20:45 | | CPB Rennes Handball | | 36-26 |  | Livry-Gargan | Salle Charles Géniaux - Rennes | | | |
| 14 Feb 2026 | | | Saint-Ouen l'Aumone
| | - | | CPB Rennes Handball | | | | |
| 21 Feb 2026 | 20:30 | | Gonfreville l'Orcher
| | - | | CPB Rennes Handball | | | | |
| 28 Feb 2026 | 20:45 | | CPB Rennes Handball | | - | | Caen | Salle Charles Géniaux - Rennes | | | |
| 14 Mar 2026 | | | Bruges | | - | | CPB Rennes Handball | | | | |
| 28 Mar 2026 | 20:45 | | CPB Rennes Handball | | - | | Chartres | Salle Charles Géniaux - Rennes | | | |
| 4 Apr 2026 | | | Nantes | | - | | CPB Rennes Handball | | | | |
| 18 Apr 2026 | | | CPB Rennes Handball | | - | | Libourne | Salle Charles Géniaux - Rennes | | | |
| 25 Apr 2026 | | | Poitiers | | - | | CPB Rennes Handball | | | | |
| 2 May 2026 | 20:45 | | CPB Rennes Handball | | - | | Union Sud Mayenne | Salle Charles Géniaux - Rennes | | | |
| 9 May 2026 | | | Hennebont-Lochrist | | - | | CPB Rennes Handball | | | | |
| 30 May 2026 | 20:45 | | CPB Rennes Handball | | - | | Rouen | Salle Charles Géniaux - Rennes | | | |
| 6 Jun 2026 | | | Livry-Gargan | | - | | CPB Rennes Handball | | | | |
