| 21 Aug 2025 | 19:15 | Amical | CPB Rennes Handball |  | 26 - 18 |  | Colombelles | Salle Charles Géniaux - Rennes | | | |
| 24 Aug 2025 | 14:00 | Amical | Saint-Sébastien sur Loire | | 18 - 28 | | CPB Rennes Handball | Salle Luc Abalo - Saint-Sebastien | | | |
| 27 Aug 2025 | 21:00 | Amical | Issy-Paris |  | 21 - 35 | | CPB Rennes Handball | Espace Sportif Claude Fortin - La Bazoges | | | |
| 30 Aug 2025 | 20:45 |  | Taulé-Carantec
|  | 13 - 35 | | CPB Rennes Handball | Salle Steredenn - Taulé | |  | |
| 6 Sep 2025 | 20:30 |  | Entente Bro Leon |  | 22 - 30 | | CPB Rennes Handball | Salle Keravel - Landivisau | | | |
| 13 Sep 2025 | 18:30 | | CPB Rennes Handball | | 28 - 25 |  | Rouen | Salle Charles Géniaux - Rennes |  | |  |
| 27 Sep 2025 | 20:45 | | CPB Rennes Handball | | 31-32 |  | Villemomble | Salle Charles Géniaux - Rennes | | | |
| 4 Oct 2025 | 20:45 | | Roz Hand'Du 29 |  | 25-20 | | CPB Rennes Handball | Halle des Sports - Rosporden | | | |
| 11 Oct 2025 | 20:45 | | CPB Rennes Handball | | 26-18 |  | Lille | Salle Charles Géniaux - Rennes | | | |
| 1 Nov 2025 | 18:00 | | Issy-Paris | | 31-24 | | CPB Rennes Handball | Cité des Sports - Issy-les-Moulineaux | | | |
| 8 Nov 2025 | 20:45 | | CPB Rennes Handball | | 22-21 |  | Paris SC | Salle Charles Géniaux - Rennes | | | |
| 15 Nov 2025 | 20:30 | | Harnes |  | 33-28 | | CPB Rennes Handball | Salle André Bigotte - Harnes | | | |
| 10 Jan 2026 | 20:45 | | CPB Rennes Handball
| | 24-23 |  | Brest | Salle Charles Géniaux - Rennes | | | |
| 17 Jan 2026 | | | Saint-Maur |  | 24-24 | | CPB Rennes Handball | Gymnase Pierre Brossolette - St Maur | | | |
| 24 Jan 2026 | 20:45 | | CPB Rennes Handball | | 29-26 |  | Octeville | Salle Charles Géniaux - Rennes | | | |
| 14 Feb 2026 | 20:45 | | CPB Rennes Handball | | - | | Bro Leon | Salle Charles Géniaux - Rennes | | | |
| 21 Feb 2026 | | | Rouen | | - | | CPB Rennes Handball | | | | |
| 28 Feb 2026 | | | Villemomble | | - | | CPB Rennes Handball | | | | |
| 14 Mar 2026 | 20:45 | | CPB Rennes Handball | | - | | Roz Hand'Du 29 | Salle Charles Géniaux - Rennes | | | |
| 21 Mar 2026 | | | Lille | | - | | CPB Rennes Handball | | | | |
| 28 Mar 2026 | 18:30 | | CPB Rennes Handball | | - | | Issy-Paris | Salle Charles Géniaux - Rennes | | | |
| 18 Apr 2026 | | | Paris SC | | - | | CPB Rennes Handball | | | | |
| 2 May 2026 | 18:30 | | CPB Rennes Handball | | - | | Harnes | Salle Charles Géniaux - Rennes | | | |
| 9 May 2026 | | | Brest | | - | | CPB Rennes Handball | | | | |
| 16 May 2026 | 20:45 | | CPB Rennes Handball | | - | | Saint-Maur | Salle Charles Géniaux - Rennes | | | |
| 30 May 2026 | | | Octeville | | - | | CPB Rennes Handball | | | | |
